Bonus Tydskrif AUTUMN 2024

ForAnimalUseOnly. Fortitude® EDC.Reg.No.:G4042 (Act 36/1947).Each 7mL syringe contains cloxacillinbenzathineequivalent to600mg cloxacillin, ina long-actingbasewith2,41%aluminiummonostearate. For fullprescribing information refer to thepackage insertapprovedby themedicines regulatoryauthority. Fullproduct informationavailable fromZoetisSouthAfrica (Pty) Ltd.Co.Reg.No.:2012/001825/07,6th Floor,NorthWing,90RivoniaRoad,Sandton,2196. PostnetSuite53,PrivateBag9976,Sandton,2146,SouthAfrica. Tel. :0800998969.www.zoetis.co.za Ref.No.:MM-30029 Please contact your local Zoetis representative to claim your body warmer. Limited sizes available. Be sure to get yours before they run out. Unfortunately we can’t guarantee that required sizes will be available. Promotion is applicable for purchases made while stock of body warmers last. Promotion is applicable to end-users and a proof of purchase is required to claim your body warmer. FOUR REASONS FOR FORTITUDE EDC: If your answer is yes, please consult your herd veterinarian to advise on the most e ective dry cow therapy for you. An over-the-counter (OTC) product will likely not be the best choice, due to their known lack of ecacy against gram-negative bacteria. This is evident from the table adapted from Bradley (2006) 1 , where ampicillin and cloxacillin, both show a poor spectrum of activity against gram-negative bacteria. In fact, look at an intra-mammary pathogen antimicrobial sensitivity test (AST) report from an accredited lab - it's likely that they don't routinely include ampicillin or cloxacillin in the panel of antibiotics tested against gram negative-bacteria, due to their known lack of ecacy. ARE GRAM NEGATIVE PATHOGENS A PROBLEM ON YOUR FARM?: Reference: 1.BradleyAJ,GreenMJ. Theuseofantibiotics in the treatmentof intramammary infectionsatdryingo.WorldBuiatricsCongress2006 -Nice, France. 2.Kietzmannetal. Tissuedistributionof cloxacillinafter intramammaryadministration in the isolatedperfusedbovineudder.BMCVeterinaryResearch20106:46. 3.CEESA salesdata -SouthAfrica2020 -2023 Specially-processed cloxacillin: Is the cloxacillin in your dry cow intramammary the right particle size for the job? The particle size of intramammary products has shown to a ect their rate and ecacy of distribution. 2 E ective antibiotic levels in the udder for up to seven (7) weeks: That's what you get from a 600 mg cloxacillin preparation. Don't sell your dry cow therapy short, make sure your cloxacillin-based dry cow therapy lasts as long as you need. Cost-e ective dry cow therapy: Consult your herd veterinarian to determine whether a narrow-spectrum dry cow intramammary is the correct option for your herd. If so, Fortitude® EDC provides a cost-e ective option for your dry cow program. Fortitude® EDC - tried and trusted: South Africa's bestselling dry cow therapy for the past 3 years! 3 1 2 3 4 TYPICALSPECTRUMOFACTIVITYOFANTIBIOTICSCOMMONLYFOUND IN DRYCOWTHERAPY DCT FORMULATIONS INTHEUK. 1 Penicillins/Penethemate Ampicillin Cloxacillin/Nafcillin Cephalonium Cefquinome Dihydrostreptomycin Framycetin/Neomycin Gram+ves +++ ++ +++ ++ ++ + ++ - - +++ ++ ++ ++ ++ - + - ++ ++ +++ +++ β -Lactamase Staphylococcus aureus Gram -ves Adapted fromBradley 1 Buy 5 + buckets of FORTITUDE® EDC (120 syringe bucket) get an awesome BODY WARMER for those early mornings C O N T A C T Y O U R L O C A L Z O E T I S R E P R E S E N T A T I V E